hdl:10013/epic.23200
publisher:10.1021/ol061317s
Stylissadines A and B: The First Tetrameric Pyrrole−Imidazole Alkaloids
Grube, Achim and Köck, Matthias
;
Contact
mkoeck [ at ] awi-bremerhaven.de
Abstract
[reaction: see text] Pyrrole-imidazole alkaloids are widely distributed in marine sponges of the orders Halichondrida and Agelasida. Chemical investigation of the Caribbean sponge Stylissa caribica led to the isolation of the first tetrameric pyrrole-imidazole alkaloids. The so-called stylissadines are the largest and most complex pyrrole-imidazole alkaloids discovered so far and are therefore a major challenge for the structure determination by NMR spectroscopy. Their isolation and structure elucidation are discussed in detail.
Item Type
Article
Authors
Grube, Achim and Köck, Matthias
;
Divisions
Programs
Helmholtz Research Programs > MARCOPOLI (2004-2008) > CO-MARCOPOLI
Helmholtz Research Programs > MARCOPOLI (2004-2008) > CO3-Chemical Interactions - ecological function and effects
Helmholtz Research Programs > MARCOPOLI (2004-2008) > CO3-Chemical Interactions - ecological function and effects
Publication Status
Published
Eprint ID
12790
DOI
https://www.doi.org/10.1021/ol061317s
Cite as
Grube, A.
and
Köck, M.
(2006):
Stylissadines A and B: The First Tetrameric Pyrrole−Imidazole Alkaloids
,
Organic Letters,
8
(21),
pp. 4675-4678
.
doi: https://www.doi.org/10.1021/ol061317s
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