Stylissadines A and B:  The First Tetrameric Pyrrole−Imidazole Alkaloids


Contact
mkoeck [ at ] awi-bremerhaven.de

Abstract

[reaction: see text] Pyrrole-imidazole alkaloids are widely distributed in marine sponges of the orders Halichondrida and Agelasida. Chemical investigation of the Caribbean sponge Stylissa caribica led to the isolation of the first tetrameric pyrrole-imidazole alkaloids. The so-called stylissadines are the largest and most complex pyrrole-imidazole alkaloids discovered so far and are therefore a major challenge for the structure determination by NMR spectroscopy. Their isolation and structure elucidation are discussed in detail.



Item Type
Article
Authors
Divisions
Programs
Publication Status
Published
Eprint ID
12790
DOI https://www.doi.org/10.1021/ol061317s

Cite as
Grube, A. and Köck, M. (2006): Stylissadines A and B:  The First Tetrameric Pyrrole−Imidazole Alkaloids , Organic Letters, 8 (21), pp. 4675-4678 . doi: https://www.doi.org/10.1021/ol061317s


Share


Citation

Research Platforms
N/A

Campaigns
N/A


Actions
Edit Item Edit Item