Isolation and Synthesis of 4-Bromopyrrole-2-carboxyarginine and 4-Bromopyrrole-2-carboxy-N(ε)-lysine from the Marine Sponge Stylissa caribica

Grube, Achim, Lichte, Ellen and Köck, Matthias ;

Contact

mkoeck [ at ] awi-bremerhaven.de

Abstract

Two new bromopyrrole alkaloids were isolated from the Caribbean sponge Stylissa caribica. The new natural products, 4-bromopyrrole-2-carboxyarginine (1) and 4-bromopyrrole-2-carboxy-N(epsilon)-lysine (2), are derivatives of amino acids linked with a 4-bromopyrrole-2-carboxylic acid. The structures were elucidated on the basis of NMR and MS/MS data and their absolute configurations assigned via synthesis.

Item Type

Article

Authors

Grube, Achim, Lichte, Ellen and Köck, Matthias ;

Divisions

AWI Organizations > Biosciences > Ecological Chemistry

Programs

Helmholtz Research Programs > MARCOPOLI (2004-2008) > CO-MARCOPOLI
Helmholtz Research Programs > MARCOPOLI (2004-2008) > CO3-Chemical Interactions - ecological function and effects

Publication Status

Published

Eprint ID

13111

DOI https://www.doi.org/10.1021/np0502746

Cite as

Grube, A. , Lichte, E. and Köck, M. (2006): Isolation and Synthesis of 4-Bromopyrrole-2-carboxyarginine and 4-Bromopyrrole-2-carboxy-N(ε)-lysine from the Marine Sponge Stylissa caribica , Journal of Natural Products, 69 (1), pp. 125-127 . doi: https://www.doi.org/10.1021/np0502746

Citation

Research Platforms

N/A

Campaigns

N/A

Actions

Edit Item