The objective of this study is to refine the understanding of recharge processes in watersheds representative for karstic semiarid areas by means of stable isotope analysis and hydrogeochemistry. The study focuses on the Granada aquifer system which is located in an intramontane basin bounded by high mountain ranges providing elevation differences of almost 2900 m. These altitude gradients lead to important temperature and precipitation gradients and provide excellent conditions for the application of stable isotopes of water whose composition depends mainly on temperature. Samples of rain, snow, surface water and groundwater were collected at 154 locations for stable isotope studies (δ18O, D) and, in the case of ground- and surface waters, also for major and minor ion analysis. Thirty-seven springs were sampled between 2 and 5 times from October 2004 to March 2005 along an altitudinal gradient from 552 masl in the Granada basin to 2156 masl in Sierra Nevada. Nine groundwater samples were taken from the discharge of operating wells in the Granada basin which are all located between 540 and 728 masl. The two main rivers were monitored every 2-3 weeks at three different altitudes. Rainfall being scarce during the sampling period, precipitation could only be sampled during four rainfall events. Calculated recharge altitudes of springs showed that source areas of mainly snowmelt recharge are generally located between 1600 and 2000 masl. The isotope compositions of spring water indicate water sources from the western Mediterranean as well as from the Atlantic without indicating a seasonal trend. The isotope pattern of the Quaternary aquifer reflects the spatial separation of different sources of recharge which occur mainly by bankfiltration of the main rivers. Isotopic signatures in the southeastern part of the aquifer indicate a considerable recharge contribution by subsurface flow discharged from the adjacent carbonate aquifer. No evaporation effects due to agricultural irrigation were detected. © 2008 Elsevier Ltd. All rights reserved.