<jats:title>Abstract</jats:title> <jats:p>The variability of an annual resolution deuterium time series from central Greenland is investigated in connection with the variability in the frequency of daily atmospheric circulation patterns in the North Atlantic region. Statistical analysis reveals that a large part of the decadal variability of the deuterium isotope record is related to decadal variability in the frequency of several identified daily circulation patterns. The study shows that these circulation patterns induce variations in the deuterium record by altering where isotopic fractionation occurs, mainly during the passage of the associated air masses over continental areas. The study identifies three significant periodic components in the deuterium isotope record at ∼12, ∼20, and ∼30 yr. It also shows that the ∼20-yr signal in the deuterium isotope record is related to the variability in the frequency of a winter circulation type. An analysis of six oxygen isotope records from central Greenland reveals decadal variations similar to the deuterium isotope record. The authors argue that high-resolution stable isotope records from Greenland ice cores can be used to obtain information about the frequency of certain daily circulation patterns during past periods.</jats:p>