hdl:10013/epic.38675
The Alkaloid Ageladine A, Originally Isolated from Marine Sponges, Used for pH-Sensitive Imaging of Transparent Marine Animals
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Ulf.Bickmeyer [ at ] awi.de
Abstract
The brominated pyrrole-imidazole Ageladine A was used for live imaging of the jellyfish (jellies) Nausithoe werneri, the sea anemone Metridium senile and the flatworm Macrostomum lignano. The fluorescence properties of Ageladine A allow for estimation of pH values in tissue and organs in living animals. The results showed that Nausithoe werneri had the most acidic areas in the tentacles and close to the mouth (pH 4-6.5), Metridium senile harbours aggregates of high acidity in the tentacles (pH 5) and in Macrostomum lignano, the rhabdoids, the gonads and areas close to the mouth were the most acidic with values down to pH 5. © 2012 by the authors; licensee MDPI.
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Article
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Helmholtz Research Programs > PACES I (2009-2013) > TOPIC 2: Coastal Change > WP 2.2: Integrating evolutionary Ecology into Coastal and Shelf Processes
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Published
Eprint ID
25168
DOI
https://www.doi.org/10.3390/md10010223
Cite as
Bickmeyer, U.
(2012):
The Alkaloid Ageladine A, Originally Isolated from Marine Sponges, Used for pH-Sensitive Imaging of Transparent Marine Animals
,
Marine Drugs,
10
(12),
pp. 223-233
.
doi: https://www.doi.org/10.3390/md10010223
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