Holocene glacimarine sedimentation associated with fast-flowing outlet glaciers draining the Greenland Ice Sheet is investigated using sedimentary and acoustic data from inner Scoresby Sund, East Greenland. Sedimentation in inner Scoresby Sund is dominated by three processes which are influenced by differences in proximity to fast-flowing outlet glaciers, extent of glacier-ice cover and fjord bathymetry: (1) sediment-gravity flow, principally in the form of turbidity currents and debris flows; (2) suspension sedimentation from turbid meltwater plumes; and (3) iceberg rafting. These processes result in texturally and sedimentologically heterogeneous lithofacies. Proportionally, fine-grained muds (laminated, stratified and massive facies) dominate cores recovered from inner Scoresby Sund, accounting for 80% of the total, whereas diamict facies account for only 15%. Abundant fine-grained muds demonstrate that meltwater flux and sedimentation is significant in this high Arctic glacimarine environment, in settings proximal to fast-flowing outlet glaciers. With increasing distance from these glacier termini, muds are replaced progressively by iceberg-rafted, coarse-grained sediment. The dominance of this iceberg-rafted sediment in outer Scoresby Sund reflects both its more distal location from fast-flowing glacier termini, and the high calving flux associated with these ice masses. Laminated muds deposited by turbidity currents and suspension settling from overflow plumes in inner Scoresby Sund are similar to lithofacies produced in temperate and subpolar glacimarine systems. This implies a similarity in sedimentation processes and resulting facies across a wide spectrum of climatically-, glaciologically- (fast-flowing and non fast-flowing ice-masses) and oceanographically-variable glacimarine settings. Recognition of laminated, fine-grained facies in the geological record therefore does not necessarily indicate a temperate palaeo-glacial setting. However, the predominance of iceberg-rafted diamict facies in ice-distal sedimentary records suggests the former presence of relatively cold environmental conditions in which iceberg-sedimentation played a dominant role. © 2001 Elsevier Science B.V.