The Alfred Wegener Institute Climate Model (AWI-CM) participates for the first time in the Coupled Model Intercomparison Project (CMIP), CMIP6. The sea ice-ocean component, FESOM, runs on an unstructured mesh with horizontal resolutions ranging from 8 to 80 km. FESOM is coupled to the Max Planck Institute atmospheric model ECHAM 6.3 at a horizontal resolution of about 100 km. Using objective performance indices, it is shown that AWI-CM performs better than the average of CMIP5 models. AWI-CM shows an equilibrium climate sensitivity of 3.2°C, which is similar to the CMIP5 average, and a transient climate response of 2.1°C which is slightly higher than the CMIP5 average. The negative trend of Arctic sea-ice extent in September over the past 30 years is 20–30% weaker in our simulations compared to observations. With the strongest emission scenario, the AMOC decreases by 25% until the end of the century which is less than the CMIP5 average of 40%. Patterns and even magnitude of simulated temperature and precipitation changes at the end of this century compared to present-day climate under the strong emission scenario SSP585 are similar to the multi-model CMIP5 mean. The simulations show a 11°C warming north of the Barents Sea and around 2°C to 3°C over most parts of the ocean as well as a wetting of the Arctic, subpolar, tropical, and Southern Ocean. Furthermore, in the northern middle latitudes in boreal summer and autumn as well as in the southern middle latitudes, a more zonal atmospheric flow is projected throughout the year.